FREQUENTLY ASKED QUESTIONS

REVATIO is a prescription medicine used to treat pulmonary arterial hypertension (PAH). PAH is a type of high blood pressure in the arteries of your lungs. REVATIO may be used in adults to improve your ability to exercise and help slow down the worsening of your physical condition.

• REVATIO may improve your ability to exercise
• REVATIO may slow down worsening changes in your physical condition

Your prescription may have been filled with a generic version instead of brand-name REVATIO. Follow the steps below to help ensure you receive the brand name your doctor prescribed and, if eligible, save on your prescription.

1. Ask Your Doctor: Ask your doctor to prescribe brand-name REVATIO and to indicate "DAW" (Dispense As Written)—or the language used in your state—on all of your REVATIO prescriptions, as appropriate.*
   *Language and requirements may vary based on your state's laws.
2. Get a Savings Card: Sign up for a Savings Card and, if eligible, you may pay as little as $0 for brand-name REVATIO.^†

   ^†Terms and conditions apply.

3. Check Your Pills: Check your pills to be sure they're brand-name REVATIO—not the generic. If you think your brand-name prescription has been filled with a generic, talk to your pharmacist.

Talk to your doctor and/or your pharmacist to ask if you should be getting brand-name REVATIO. For tips on having that conversation, download the BRAND Savings Tip Sheet.

Check your pills for the distinctive shape and markings of brand-name REVATIO.

The REVATIO Savings Card allows eligible patients to pay as little as $0 each month for brand-name REVATIO—and could save up to $12,000 a year. If you have a prescription for brand-name REVATIO, you can use the card for every fill through December 31, 2024.*

*Terms and conditions apply.

There are 2 ways to use the card immediately. Once you’ve activated your Savings Card, you can either:

• Bring a printed copy of it to the pharmacy
• Show it to your pharmacist on your phone

You can keep this card with you and continue to save on each fill for REVATIO through December 31, 2024.

To be eligible to use a REVATIO Savings Card:

• You do not have insurance from any Federal Healthcare Program (including Medicare, Medicaid, TRICARE, or any other state or federal medical pharmaceutical benefit program or pharmaceutical assistance program)
• You and your spouse/partner are both not over age 65 and retired
• You do not receive Social Security Disability Insurance (SSDI) or any other Social Security Administration (SSA) benefits
• Neither you, your spouse nor your parents are on active military duty and if so, you are not covered by their military health insurance
• You do not have End-Stage Renal Disease (ESRD)
• You are over the age of 18
• You agree to the Terms and conditions

To learn the full details of who is eligible, please see the full Terms and conditions.

To get a Savings Card, register here and then download your card or have it sent to you via email.

You can activate your Savings Card here.

The REVATIO Savings Card can only be used for new prescriptions that are filled after you have activated the card.

Yes, for reimbursement when using a nonparticipating pharmacy: Pay for your REVATIO prescription, and mail a copy of the original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: REVATIO Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your REVATIO Savings Card, your name, and mailing address. Please expect up to 4 to 6 weeks for reimbursement.

Yes, for reimbursement when using the REVATIO Savings Card through a mail-order pharmacy: Pay for your REVATIO prescription, and mail a copy of the original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: REVATIO Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your REVATIO Savings Card, your name, and mailing address. Please expect up to 4 to 6 weeks for reimbursement.

- Take or give REVATIO exactly as your healthcare provider tells you

- Your healthcare provider may change your dose of REVATIO as needed. Do not change your dose or stop taking REVATIO without talking to your healthcare provider

- REVATIO may be prescribed to you as REVATIO tablets or REVATIO oral suspension

- Take your prescribed dose of REVATIO tablets or oral suspension 3 times a day

- See the detailed Instructions for Use that comes with REVATIO oral suspension for information on how to take or give REVATIO oral suspension. REVATIO oral suspension will be mixed for you by your pharmacist. Do not mix REVATIO oral suspension with other medicine or flavoring

- If you take too much REVATIO, call your healthcare provider or go to the nearest hospital emergency room right away

REVATIO may cause serious side effects, including:

• See “What is the most important information I should know about REVATIO?”
• Decreased blood pressure. REVATIO may cause low blood pressure that last for a short time. If you take medicines to treat high blood pressure, your healthcare provider should monitor your blood pressure during treatment with REVATIO.
• Decreased eyesight or permanent loss of vision in one or both eyes can be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). Most people who develop NAION have certain risk factors. You can ask your healthcare provider if you have questions about risk factors for NAION. If you notice a sudden decrease or loss of vision in one or both eyes during treatment with REVATIO, contact your healthcare provider right away.
• Sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. If you notice a sudden decrease or loss of hearing during treatment with REVATIO, contact your healthcare provider right away.
• In men, an erection that lasts for more than 4 hours (priapism). If you have an erection, with or without pain, that lasts more than 4 hours, contact your healthcare provider or get emergency medical help right away. A painful erection that lasts more than 6 hours must be treated right away or you can have lasting damage to your penis, including the inability to have erections.

The most common side effects of REVATIO in adults include:

• nosebleeds
• headache
• upset stomach
• getting red or hot in the face (flushing)
• arm or leg pain
• muscle aches and pain
• back pain
• diarrhea

These are not all the possible side effects of REVATIO. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Never take REVATIO with any nitrate or guanylate cyclase stimulator medicines.

• Your blood pressure could drop quickly to an unsafe level.

Nitrates include:

• Medicines that treat chest pain (angina)
• Nitroglycerin in any form, including tablets, patches, sprays, and ointments
• Isosorbide mononitrate or dinitrate
• Street drugs called "poppers" (amyl nitrate, butyl nitrate or nitrite)

Guanylate cyclase stimulators include:

• Riociguat, a medicine that treats pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Ask your doctor or pharmacist if you are not sure if you are taking a nitrate or a guanylate cyclase stimulator medicine.

• REVATIO contains the same medicine as VIAGRA^®    (sildenafil), which is used to treat erectile dysfunction (impotence). Do not take REVATIO with VIAGRA or other PDE5 inhibitors

PAH is a specific type of pulmonary hypertension that is caused when the tiny arteries in your lung become thickened and narrowed. This blocks the blood flow through your lungs which raises the blood pressure in the lungs and causes your heart to work harder to pump your blood through those narrowed arteries. Over time, your heart loses the ability to effectively pump blood throughout your body.

In the early stages of PAH, you may not notice any symptoms at all. As the disease progresses, you will start to experience symptoms common to other lung diseases. The most common symptoms of PAH are:

• Increased shortness of breath
• Fatigue
• Edema, or swelling of the feet, legs and eventually the abdomen and neck
• Dizziness and fainting spells
• Chest pain
• Heart palpitations (racing or pounding)
• Lips and fingers turning blue
• Cough
• Hoarseness